abstract：:Enterovirus 71 (EV71) is the major causative agent of hand foot and mouth disease. And EV71 causes epidemics worldwide, particularly in the Asia-Pacific region. Unfortunately, currently there is no approved vaccine or antiviral drug for EV71-induced disease prevention and therapy. In screening for anti-EV71 candidates...

journal_title：Journal of Asian natural products research

authors： Wang HQ,Meng S,Li ZR,Peng ZG,Han YX,Guo SS,Cui XL,Li YH,Jiang JD

更新日期：2013-01-01 00:00:00

abstract：:Two new phthalates bis(2-ethylundecyl)phthalate and bis(2-ethyltridecyl)phthalate have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei along with one known compound β-amyrin. The structures of the two new compounds and β-amyrin were assigned on the basis of their ¹H and ¹³C NMR s...

journal_title：Journal of Asian natural products research

authors： Hussain J,Rehman NU,Hussain H,Ali L,Al-Harrasi A

更新日期：2012-01-01 00:00:00

abstract：:Two new guaianolides artemanomalides A and B were isolated from the aerial parts of Artemisia anomala S. Moore. Their structures were characterized as 2-oxo-5α, 10α-dihydroxy-guaia-3-en-1α, 6β, 7α, 11β H-12, 6-olide (1) and 8α-acetoxy-2-oxo-5α, 10α-dihydroxy-guaia-3, 11(13)-dien-1α, 6β, 7αH-12, 6-olide (2) on the basi...

journal_title：Journal of Asian natural products research

authors： Hu ZH,Zhang P,Huang DB,Wu JZ

更新日期：2012-01-01 00:00:00

abstract：:A new chiro-inositol ester, 4-hydroxyphenylacetyl-3-d-chiro-inositol ester (1), was isolated from the whole plants of Prenanthes macrophylla Franch., along with 10 known compounds, 4-hydroxyphenylacetic acid (2), trans-ethyl caffeate (3), cis-ethyl caffeate (4), protocatechualdehyde (5), luteolin (6), luteolin-7-O-β-d...

journal_title：Journal of Asian natural products research

authors： Zhang YH,Chen YS,Lin XY,Chen SW,Li P,Zhong LJ

更新日期：2012-01-01 00:00:00

abstract：:A bioassay-guided phytochemical fractionation of the methanol extract of the Morus alba root barks led to the isolation of two chalcone-derived Diels-Alder adducts (1 and 2). Their structures were elucidated as kuwanon J 2,4,10″-trimethyl ether (1) and kuwanon R (2) by means of spectroscopic methods. Both compounds st...

journal_title：Journal of Asian natural products research

authors： Phung TX,Tran TH,Dan TT,Chau VM,Hoang TH,Nguyen TD

更新日期：2012-01-01 00:00:00

abstract：:Nine new fatty acid derivatives, including seven methoxylated (1, 2, and 4-8) and two hydroxylated (3 and 9) fatty acids, have been isolated from the ethanol extract of the stem bark of Fraxinus sieboldiana. Their structures were determined by spectroscopic methods including IR, MS, 1D, and 2D NMR experiments. The 3- ...

journal_title：Journal of Asian natural products research

authors： Lin S,Zhang YL,Liu MT,Zi JC,Gan ML,Song WX,Fan XN,Wang SJ,Yang YC,Shi JG

更新日期：2012-01-01 00:00:00

abstract：:Two new neolignan glucosides named (7S, 8R)-4,7,9,9'-tetrahydroxy-3,3'-dimethoxyl-7'-oxo-8-4'-oxyneolignan-4-O-β-D-glucopyranoside and (7'S, 8'R, 8S)-4,4',9'-trihydroxy-3,3'-dimethoxy-7',9-epoxylignan-7-oxo-4-O-β-D-glucopyranosyl-4'-O-β-D-glucopyranoside, together with two small molecular peptides named 3-benzyl-6-(1-...

journal_title：Journal of Asian natural products research

authors： Yang YN,Zhang F,Feng ZM,Jiang JS,Zhang PC

更新日期：2012-01-01 00:00:00

abstract：:Two new metabolites, pyrenocine J (1) and pyrenochaetic acid D (2), together with two known metabolites, pyrenocine A (3) and pyrenochaetic acid A (4), were isolated from a soil fungus, Curvularia affinis strain HS-FG-196. Their structures were established by extensive spectroscopic analysis. Compound 1 showed cytotox...

journal_title：Journal of Asian natural products research

authors： Zhang H,Mao LL,Qian PT,Shan WG,Wang JD,Bai H

更新日期：2012-01-01 00:00:00

abstract：:Two new sesquiterpene derivatives, (+)-8β-hydroxy-longicamphenylone (1) and 11β-hydroxy-13-isopropyl-dihydrodehydrocostus lactone (2), were isolated from Chinese eaglewood. Their structures were elucidated on the basis of spectroscopic analyses including HR-ESI-MS, (1)H and (13)C NMR, DEPT, (1)H-(1)H COSY, HSQC, HMBC,...

journal_title：Journal of Asian natural products research

authors： Yang L,Qiao LR,Zhang JJ,Dai JG,Guo SX

更新日期：2012-01-01 00:00:00

abstract：:A new triterpenoid, 11α,12α-epoxy-3β-hydroxy-24-nor-olean-4(23)-en-28,13β-olide (1), and a new glycoside, benzyl 2-O-β-d-apiofuranosyl-(1 → 2)-β-d-glucopyranosyl benzoate (2), together with eight known triterpenoids (3-10), were isolated from Pilea cavaleriei subsp. cavaleriei. Their structures were established on the...

journal_title：Journal of Asian natural products research

authors： Ren HC,Qin RD,Wang Q,Cheng W,Zhang QY,Liang H

更新日期：2012-01-01 00:00:00

abstract：:Two new cycloartane glycosides were isolated from the aerial parts of Thalictrum fortunei (Ranunculaceae). The chemical structures of these compounds were elucidated as 3-O-β-D-glucopyranosyl (1 → 4)-β-d-fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,30-tetraol 26-O-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl (1 →...

journal_title：Journal of Asian natural products research

authors： Zhang XT,Ma SW,Jiao HY,Zhang QW

更新日期：2012-01-01 00:00:00

abstract：:A new spirocyclic compound named (2S, 5S, 7S)-3α-hydroxyl-exogonic acid (1) was isolated from the liquid culture of entomogenous fungus Isaria cateniannulata. The structure and relative stereochemistry of 1 were elucidated by extensive spectroscopic analysis and by comparison of its NMR data with those of known compou...

journal_title：Journal of Asian natural products research

authors： Yang XL,Li ZZ,Zhang S,Yu H,Zhu HJ,Luo DQ

更新日期：2012-01-01 00:00:00

abstract：:Epoxyeicosatrienoic acids (EETs) and their regulating enzyme soluble epoxide hydrolase (sEH) have been associated with ischemic stroke. Salvianolic acid A (SAA) is proved to display potent cerebroprotection. However, little information is available about the link between them. This study aimed to investigate whether S...

journal_title：Journal of Asian natural products research

authors： Wang SB,Pang XB,Zhao Y,Wang YH,Zhang L,Yang XY,Fang LH,Du GH

更新日期：2012-01-01 00:00:00

abstract：:A chemical investigation of the endemic relict shrub Tetraena mongolica led to the isolation of four new triterpenes: 11α,12α:13β,28-diepoxyoleanane-3β-yl trans-caffeate (1), 3β-hydroxy-11α,12α-epoxyoleanane-28-al (2), olean-11-en-28-al-3β-yl trans-caffeate (3), and 28-acetoxy-olean-12-en-3β-yl trans-caffeate (4). The...

journal_title：Journal of Asian natural products research

authors： Tang SA,Ding LL,Zhai HY,Qin N,Duan HQ

更新日期：2012-01-01 00:00:00

abstract：:From the EtOH extract of the flowers of Camellia nitidissima Chi, a new acylated flavonoid glycoside, quercetin 7-O-(6"-O-E-caffeoyl)-β-D-glucopyranoside (1), has been isolated, together with three known flavonoids: quercetin (2), quercetin 3-O-β-D-glucopyranoside (3), and quercetin 7-O-β-D-glucopyranoside (4). Their ...

journal_title：Journal of Asian natural products research

authors： Peng X,Yu DY,Feng BM,Wang YQ,Shi LY

更新日期：2012-01-01 00:00:00

abstract：:Two new meroterpenes, guignardone D (1) and guignardone E (2), were isolated from endophytic fungus A1 of Scyphiphora hydrophyllacea Gaertn. F. Their structures were established based on spectroscopic methods including 1D and 2D NMR (HMQC, (1)H-(1)H COSY, HMBC, and ROESY). ...

journal_title：Journal of Asian natural products research

authors： Zheng B,Zeng YB,Dai HF,Zuo WJ,Guo ZK,Yang T,Zhong HM,Mei WL

更新日期：2012-01-01 00:00:00

abstract：:Chemical examination of the methanolic extract from the stem bark of Daphne feddei led to the isolation of three new dicoumarin glucosides (1-3), and eight known coumarins, dicoumarins and dicoumarin glucosides. Their structures were elucidated by extensive analysis of spectral data and comparison with the literature ...

journal_title：Journal of Asian natural products research

authors： Liang S,Feng Y,Tian JM,Lu M,Xiong Z,Zhang WD

更新日期：2011-12-01 00:00:00

abstract：:A new ester, 2-(4'-hydroxyphenyl)ethyl dotriacontanoate (1), and a new inseparable mixture of octacosan-1,28-dioldiferulate and triacontan-1,30-dioldiferulate (2) were isolated from the stem barks of Stereospermum acuminatissimum, along with 24 known compounds including 4 triterpenoids, 11 anthraquinones, 2 lignans, 3...

journal_title：Journal of Asian natural products research

authors： Sob SV,Wabo HK,Tang CP,Tane P,Ngadjui BT,Ye Y

更新日期：2011-12-01 00:00:00

abstract：:A new selaginellin derivative, selaginellin M (1), together with one known compound, selaginellin E (2), was isolated from Selaginella pulvinata. The structure of the new compound was elucidated and named as (R,S)-4-((4'-hydroxy-4-((2-hydroxyethoxy)methyl))-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)me...

journal_title：Journal of Asian natural products research

authors： Xu KP,Zou H,Liu GR,Long HP,Li J,Li FS,Zou ZX,Kuang JW,Xie X,Tan GS

更新日期：2011-10-01 00:00:00

abstract：:Gamboge is a dry resin secreted from Garcinia hanburryi, and gambogenic acid (GNA) is one of the main active compounds of gamboge. We have previously demonstrated the anticancer activity of GNA in A549 cells and pointed out its potential effects in anticancer therapies. Previous studies reported that GNA induced apopt...

journal_title：Journal of Asian natural products research

authors： Cheng H,Su JJ,Peng JY,Wang M,Wang XC,Yan FG,Wang XS,Li QL

更新日期：2011-10-01 00:00:00

abstract：:Glycyrrhetinic acid (GA) is an active component of licorice root that has long been used as a herbal medicine for the treatment of peptic ulcer, hepatitis, and pulmonary and skin diseases in Asia and Europe. In this study, we analyzed the effect of GA extracted from Glycyrrhiza uralensis Fisch. on the expression of To...

journal_title：Journal of Asian natural products research

authors： Peng LN,Li L,Qiu YF,Miao JH,Gao XQ,Zhou Y,Shi ZX,Xu YL,Shao DH,Wei JC,Ma ZY

更新日期：2011-10-01 00:00:00

abstract：:Two new monoterpenoid glycosides, α-(E)-acaridiol 8-O-β-d-glucopyranoside (1) and α-(E)-acaridiol 9-O-β-d-glucopyranoside (2), as well as a new thiophen, 2-acetyl-3-hydroxy-5-(prop-1-ynyl)thiophen 3-O-β-d-glucopyranoside (3), were isolated from the roots of Eupatorium chinense. Their structures were determined on the ...

journal_title：Journal of Asian natural products research

authors： Wang WJ,Wang Y,Zhang QW,Zhang XQ,Yang TT,Dai Y,Wang L,Zhang LH,Ye WC

更新日期：2011-09-01 00:00:00

abstract：:Paniculacin (1), a new coumarin derivative, has been isolated from the ethyl acetate soluble fraction of the ethanolic extract of Murraya paniculata along with umbelliferone, scopoletin, 4-hydroxybenzoic acid, trans-cinnamic acid, and β-sitosterol. Their structures were elucidated on the basis of spectral data. ...

journal_title：Journal of Asian natural products research

authors： Saeed S,Shah S,Mehmood R,Malik A

更新日期：2011-08-01 00:00:00

abstract：:Three new acetylated anthraquinone glycosides (1-3) were isolated from the seed of Cassia obtusifolia, together with one parent anthraquinone glycoside (1a). Their structures were determined on the basis of spectroscopic methods and physicochemical properties as obtusifoline-2-O-β-d-2, 6-di-O-acetylglucopyranoside (1)...

journal_title：Journal of Asian natural products research

authors： Wu XH,Cai JJ,Ruan JL,Lou JS,Duan HQ,Zhang J,Cheng CR,Guo DA,Wu ZY,Zhang YW

更新日期：2011-06-01 00:00:00

abstract：:A new furanocoumarin named lucidafuranocoumarin A (7) together with 13 known coumarins (1-6, 8-14) and four known alkaloids (15-18) was isolated from the roots of Feroniella lucida. Their structures were elucidated on the basis of spectroscopic analysis. Some of the isolates were evaluated for their biological activit...

journal_title：Journal of Asian natural products research

authors： Sripisut T,Cheenpracha S,Laphookhieo S

更新日期：2011-06-01 00:00:00

abstract：:A rare type of phenolic compound, namely, planchol E (1), was isolated from the cones and seeds of Pinus yunnanensis together with 16 known abietane diterpenoids (2-17). The structure of planchol E was established on the basis of extensive spectroscopic analysis, and it was found that the new compound did not show cyt...

journal_title：Journal of Asian natural products research

authors： Lei T,Li Y,Li DM,Liu GM,Liu JK,Wang F

更新日期：2011-05-01 00:00:00

abstract：:Pueraria lobata flower is a medicinal herb for treating intoxication, hepatic, and gastrointestinal tract lesions induced by alcohol. This study aims to investigate the isoflavonoid glycosides in P. lobata flowers. Two new isoflavone compounds were isolated from the extract of P. lobata flowers. Their structures were ...

journal_title：Journal of Asian natural products research

authors： Yu YL,Liao YT,Li X,Ye Y,Ke CQ,Li XQ,Yang XZ,Yao MC

更新日期：2011-04-01 00:00:00

abstract：:Two new selaginellin derivatives, selaginellins K (1) and L (2), were isolated from Selaginella tamariscina (Beauv.) Spring and characterized as 2-formyl-4,4'-dihydroxy-3-[(4-hydroxyphenyl)ethynyl]biphene and 4,4'-dihydroxy-2-methyl-3-[(4-hydroxyphenyl)ethynyl]biphene on the basis of their spectroscopic data including...

journal_title：Journal of Asian natural products research

authors： Xu KP,Zou H,Li FS,Xiang HL,Zou ZX,Long HP,Li J,Luo YJ,Li YJ,Tan GS

更新日期：2011-04-01 00:00:00

abstract：:Two new dammarane-type triterpene saponins were isolated from the red American ginseng. The new saponins were named as pseudoginsenoside G(1) and pseudoginsenoside G(2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 3-O-[β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl]-dammar-...

journal_title：Journal of Asian natural products research

authors： Liu JP,Lu D,Li PY

更新日期：2011-03-01 00:00:00

abstract：:The investigation of chemical constituents from the branches of Calophyllum inophyllum Linn led to the isolation of a new prenylated xanthone, named caloxanthone Q (1), together with three known compounds, 2-deprenylrheediaxanthone B (2), jacareubin (3), and 6-deoxyjacareubin (4). Their structures were completely eluc...

journal_title：Journal of Asian natural products research

authors： Wei DJ,Mei WL,Zhong HM,Zeng YB,Wu XD,Dai HF

更新日期：2011-03-01 00:00:00

abstract：:Microbial transformation of oleanolic acid (1) was carried out. Six transformed products (2-7) from 1 by Alternaria longipes and three transformed products (8-10) from 1 by Penicillium adametzi were isolated. Their structures were elucidated as 2α,3α,19α-trihydroxy-ursolic acid-28-O-β-d-glucopyranoside (2), 2α,3β,19α-...

journal_title：Journal of Asian natural products research

authors： Liu DL,Liu Y,Qiu F,Gao Y,Zhang JZ

更新日期：2011-02-01 00:00:00

abstract：:By various chromatographic methods, one new phenylpropanoid, acanthopanic acid (1), and three known compounds, 1,2-O-dicaffeoylcyclopenta-3-ol (2), (4S)-α-terpineol 8-O-β-D-glucopyranoside (3), and rutin (4), were isolated from the methanol extract of the Acanthopanax koreanum leaves. Their structures were elucidated ...

journal_title：Journal of Asian natural products research

authors： Nhiem NX,Kim KC,Kim AD,Hyun JW,Kang HK,Van Kiem P,Van Minh C,Thu VK,Tai BH,Kim JA,Kim YH

更新日期：2011-01-01 00:00:00

abstract：:Two new acetylated flavan glycosides (2S,4R)-4,5,7-trihydroxy-4'-methoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (1) and (2S,4R)-5,7-dihydroxy-4,4'-dimethoxy-6,8-dimethylflavan-5-O-β-D-6-acetylglucopyranoside-7-O-β-D-glucopyranoside (2) were isolated from the rhizomes of Abacopteris ...

journal_title：Journal of Asian natural products research

authors： Zhao ZX,Ruan JL,Jin J,Zhu CC,Lin CZ

更新日期：2010-12-01 00:00:00

abstract：:Pharmacologically motivated natural product investigations have yielded a large variety of structurally unique lead compounds with interesting biomedical properties, but the natural roles of these molecules often remain unknown. In the present investigation, a series of benzyl substituted-flavone derivatives have been...

journal_title：Journal of Asian natural products research

authors： Kumar GS,Tiwari AK,Rao VR,Prasad KR,Ali AZ,Babu KS

更新日期：2010-11-01 00:00:00

abstract：:Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂, and ginsenoside Rh₁₃. Their structures were elucidated as (20S)-3β,6α,12β,20-tetrahydroxydammara-25-ene-2...

journal_title：Journal of Asian natural products research

authors： Liu GY,Li XW,Wang NB,Zhou HY,Wei W,Gui MY,Yang B,Jin YR

更新日期：2010-10-01 00:00:00

abstract：:Two new furostanol glycosides, ophiopogonins H (1) and I (2), were isolated from the fibrous root of Ophiopogon japonicus. The structures of 1 and 2 were established as (25R)-26-[(O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl)]-22α-hydroxyfurost-5-ene-3-O-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside and (25R)-26-[(...

journal_title：Journal of Asian natural products research

authors： Duan CL,Ma XF,Jiang Y,Liu JX,Tu PF

更新日期：2010-09-01 00:00:00

abstract：:A new diimide derivative, named (-)-byssochlamic acid bisdiimide (1), was isolated from the mixed broth of two mangrove fungi (strain no. K38 and E33) from the South China sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, including 1D and 2D NMR (COSY, HMQC, and HMBC) and semi-synthe...

journal_title：Journal of Asian natural products research

authors： Li CY,Ding WJ,Shao CL,She ZG,Lin YC

更新日期：2010-09-01 00:00:00

abstract：:Three new polyoxypregnane glycosides, tenacigenosides F-H (1-3), were isolated from the stems of Marsdenia tenacissima. The structures of these new compounds were elucidated from 1D and 2D NMR spectra, as well as from HR-MS and acid hydrolysis. ...

journal_title：Journal of Asian natural products research

authors： Wang XL,Peng SL,Ding LS

更新日期：2010-08-01 00:00:00

abstract：:Barlericin, the new neolignan diglycoside, has been isolated from the n-butanol soluble sub-fraction of Barleria acanthoides along with dehydrodiconiferyl alcohol 12-O-beta-D-glucopyranoside (2), reported for the first time from the genus Barleria. Their structures have been assigned on the basis of spectral studies. ...

journal_title：Journal of Asian natural products research

authors： Karim A,Noor AT,Malik A

更新日期：2010-08-01 00:00:00

abstract：:Ten (1-10) irritant and mild co-carcinogenic diterpene esters were isolated from the latex of Euphorbia cauducifolia L. using bioassay-guided countercurrent distribution and other chromatographic techniques. The isolated compounds were characterized on the basis of spectroscopic results and mass measurements. As an ou...

journal_title：Journal of Asian natural products research

authors： Baloch IB,Baloch MK

更新日期：2010-07-01 00:00:00